This is the year for imaging-based cytometry, and researchers around the world are using AI and morphological features to make ground breaking discoveries. At the forefront of this movement is the ThinkCyte VisionSort, a microfluidics-based cell sorter that uses “Ghost Cytometry” to make us question “Do we even need fluorophores anymore?”.

Below is a short list of how other researchers are using the ThinkCyte Vision Sort:

• Ghost Cytometry: The paper that started it all
  https://www.science.org/doi/10.1126/science.aan0096
• CRISPR screening using ghost cytometry:
  https://www.cell.com/cell-reports-methods/fulltext/S2667-2375(24)00062-6
• Label-free enrichment of human pluripotent stem cells:
  https://www.cell.com/stem-cell-reports/fulltext/S2213-6711(23)00463-0
• A Label-free Method to Determine the Glycolytic State of T cells for CAR T Generation
  https://thinkcyte.com/download/file/2063/?tmstv=1708362437
• Label-free Macrophage Subtyping
  https://thinkcyte.com/download/file/1339/?tmstv=1701206439
• Classification of mitochondrial morphology in activated T cells
  https://thinkcyte.com/wp-content/uploads/TCY-AN-016.24.1-MITOCHONDRIAL-TCELLS-1.pdf

The following overview on the ThinkCyte VisionSort was presented to users of the MSU Flow Cytometry Core Facility on June 19th, 2024: Link